Work of scaner mostly depends on it's type - SCSI/LPT/USB/..., because TWAIN-interface is supported. Also you can find information about scanners and OS/2 here.
System requirements of eComStation are low. It works on netbooks and old Pentium. (Of course, it works on modern 2- / 4- or 8-core computers). eCS 2.0 what's new?